MRFF – Clinical Trials Activity Initiative – 2025 International Clinical Trial Collaborations Grant Opportunity

This initiative aims to boost clinical trial activity in Australia by supporting international collaborative clinical trials.

Objectives:

• Promote Australian participation in international investigator-initiated clinical trials by establishing and coordinating trial sites in Australia.
• Generate high-quality evidence on the effectiveness of novel health treatments, drugs, or devices in usual care settings to inform decisions on their use in Australia.
• Improve health and wellbeing of Australians by increasing access to evidence-based, effective healthcare through new clinical trials.

Target Beneficiaries:

• Approved MRFF Eligible Organisations in Australia.
• Researchers proposing clinical trials in Australia in collaboration with international partners.
• Australian patients who gain access to relevant clinical trials.

Application Process:

• Applications must be submitted electronically via NHMRC’s online system (Sapphire).
• Proposals must involve clinical trials that have not yet commenced recruitment at Australian sites.
• Applicants should consult the MRFF Eligible Organisation submitting the application for any specific requirements.
• Two rounds for minimum data submission: 2 July 2025 and 10 December 2025.
• Questions deadline: 23 July 2025 and 28 January 2026 respectively.

Key Features:

• Total funding pool of AUD 13 million.
• Individual grants range from AUD 0 to 3 million.
• Grant activity timeframe is within seven years of grant schedule execution.
• Administered by NHMRC on behalf of the Australian Government Department of Health and Aged Care.
• Supports trials that provide evidence to support healthcare delivery decisions in Australia.
• Encourages international collaboration to bring global trials to Australian patients.

This initiative is designed to strengthen Australia's clinical trial landscape by fostering international partnerships and enhancing patient access to innovative treatments through rigorous clinical research.

For more details, see the official NHMRC MRFF page.